Noxilizer, Inc.

Noxilizer, Inc. is a manufacturer and developer of ultra-low temperature nitrogen dioxide (NO2) sterilization technology based in Hanover, Maryland. The company provides nitrogen dioxide sterilizers and contract sterilization services for pharmaceutical, biotechnology, and medical device manufacturers. Designed as an alternative to ethylene oxide (EtO) and vaporized hydrogen peroxide (VHP), Noxilizer's proprietary platform operates at ultra-low temperatures between 10°C and 30°C and minimal pressure requirements. Its primary equipment offerings include commercial NO2 sterilizer systems such as the UltraNox platform, alongside custom quartz biological indicators for process validation. Noxilizer delivers comprehensive technical services including feasibility and validation studies, packaging design consulting, and regulatory validation support. The ultra-low temperature process preserves the structural and functional integrity of sensitive drug-device combination products, prefilled syringes, and ophthalmic delivery devices. Operating with short cycle times of six to twelve hours and rapid in-chamber aeration, the company enables healthcare product manufacturers to optimize supply chain timelines and accelerate product batch release.