Synesis is a European public-private consortium, made up of Italian and German SMEs and of public research and technological development Institutes: the Italian CNR (National Research Council) and the German Fraunhofer Gesellschaft. Dedicated to industrial research and technology transfer activities for the innovation of manufacturing processes and products, Synesis operates to facilitate the transfer of technology arising from research to industry, exploiting the most challenging results of R&D efforts through the development of new value added industrial solutions, in partnership with high tech enterprises operating in various sectors of manufacturing. The intended result is fostering an increase in competitiveness of manufacturing industries through innovation of both processes and products, allowing a more efficient and effective management of plants and resources and better response to identified market needs. The integration of results of research activities with the extensive range of established know-how allows Synesis to offer a full package of industrial competences to partner enterprises, combining technological innovation with organizational and sustainability aspects. Operating on a vast spectrum of intervention areas, such as Control and automation systems, Prototyping and production of machines for special processes, Simulation and optimisation techniques and Industrial production sustainability and Life Cycle Assessment, Synesis has a continued involvement in European research projects in partnership with international centres of excellence.